Results for 5an8

PDB: 5an8 Gene name: TRPV2 UniProt: G1SNM3_RABIT EMD: emd_6455.gz
EMD-6455

Membrane mimetics: amphipol; A8-35; eluted with DDM, POPC, POPE, POPG


Cross-sections at different angles

green: density, gray dots: atoms from the all-atom model, lines: membrane boundaries defined by TMDET



The determined edges at each slice and their comparison to TMDET

dots: edges of the gradient, triangles: outliers,
dashed and solid lines: membrane boundaries defined by TMDET and MemBlob ( mean(Zi) decreased by the thickness of the interface region (8 Å))
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Manual settings applied

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Boundary values (averages for MemBlob)


Z (PDBTM) Z (MemBlob) Z - 8
End1 14.25 23.83 15.83
End0 -14.25 -28.44 -20.44

Mapping the results to the structure

You can move/scale/rotate the structure. Blue: a.a. facing to bulk water; magenta: interface region; green: a.a. interacting with the hydrophobic membrane core; yellow: burried a.a. red: a.a. with an invisible side chain and non-protein molecules, for which DSSP cannot return SASA
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